DEVELOPMENT AND VALIDATION OF A NOVEL LIPID METABOLISM-RELATED GENE PROGNOSTIC SIGNATURE AND CANDIDATE DRUGS FOR PATIENTS WITH BLADDER CANCER

Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

Abstract Background Bladder cancer (BLCA) is a common cancer associated with an unfavorable prognosis.Increasing numbers of studies have demonstrated that lipid metabolism affects the progression and treatment of tumors.Therefore, this study aimed to explore the function and prognostic value of lipid metabolism-related genes in patients with bladde

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Predicting PTSD using the New York Risk Score with genotype data: potential clinical and research opportunities

Joseph A Boscarino,1,2 H Lester Kirchner,3,4 Stuart N Hoffman,5 Porat M Erlich1,4 1Center for Health Research, Geisinger Clinic, Danville, 2Department of Psychiatry, Temple University School of Medicine, Philadelphia, 3Division of Medicine, Geisinger Clinic, Danville, 4Department of Medicine, Temple University School of Medicine, Philadelphia, 5Dep

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Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading to alveolar destruction in the lungs.Mitotic arrest deficient 2 like 1 (MAD2L1) is a component

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